You can use the MS SQL extension (see the PHP manual below). I've never used it myself, so your mileage may vary.

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I have only done it from Linux, but it is probably easier with IIS.

Use phpInfo() to make sure you have MSSql Support.
<?
$MSDBConn = mssql_connect($IP_ADDR,$Username,$Passwd...
mssql_select_db($DB_Name);
$sql = "SELECT * FROM TABLE";
$res = mssql_query($sql);
while($row = mssql_fetch_object($res))
{
echo "$r->Column_Name";
}
?>

You can also create a system ODBC connection, then you just use the odbc functions, but you are better off using the mssql functions.

How do I connect PHP and IIS webserver to an MS SQL database?